亚洲一区二区三区麻豆毛片|日韩亚洲美女一区二区在线视频|久久精品一区二区三区日韩|中文字幕在线日韩人妻精品

免費(fèi)咨詢(xún)熱線:
15522676233

產(chǎn)品分類(lèi)

Product Category

相關(guān)文章

Related Articles
產(chǎn)品中心
首頁(yè) > 產(chǎn)品中心 > > 代理 > 艾伏尼布 Ivosidenib

艾伏尼布 Ivosidenib

簡(jiǎn)要描述:艾伏尼布 Ivosidenib
Ivosidenib, also known as AG-120 and RG-120, is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), with potential antineoplastic activity.

  • 產(chǎn)品型號(hào):型號(hào)齊全
  • 廠商性質(zhì):代理商
  • 更新時(shí)間:2023-07-12
  • 訪  問(wèn)  量:1027
詳情介紹

Product Name: 艾伏尼布 Ivosidenib

Description: Ivosidenib, also known as AG-120 and RG-120, is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), with potential antineoplastic activity. Ivosidenib specifically inhibits a mutated form of IDH1 in the cytoplasm, which inhibits the formation of the oncometabolite, 2-hydroxyglutarate (2HG). This may lead to both an induction of cellular differentiation and an inhibition of cellular proliferation in IDH1-expressing tumor cells.

Name: Ivosidenib
CAS#: 1448347-49-6 (Ivosidenib)
Chemical Formula: C28H22ClF3N6O3
Exact Mass: 582.1394
Molecular Weight: 582.97
Elemental Analysis: C, 57.69; H, 3.80; Cl, 6.08; F, 9.78; N, 14.42; O, 8.23

Synonym: Ivosidenib, AG-120; AG120; AG 120; RG-120; RG 120; RG120; Tibsovo;

IUPAC/Chemical Name: (S)-N-((S)-1-(2-chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethyl)-1-(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide

InChi Key: WIJZXSAJMHAVGX-DHLKQENFSA-N

InChi Code: InChI=1S/C28H22ClF3N6O3/c29-21-4-2-1-3-20(21)25(26(40)36-18-11-28(31,32)12-18)37(19-10-17(30)14-34-15-19)27(41)22-5-6-24(39)38(22)23-9-16(13-33)7-8-35-23/h1-4,7-10,14-15,18,22,25H,5-6,11-12H2,(H,36,40)/t22-,25-/m0/s1

SMILES Code: O=C([C@H](CC1)N(C2=NC=CC(C#N)=C2)C1=O)N([C@@H](C3=CC=CC=C3Cl)C(NC4CC(F)(F)C4)=O)C5=CC(F)=CN=C5

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001




留言框

  • 產(chǎn)品:

  • 您的單位:

  • 您的姓名:

  • 聯(lián)系電話:

  • 常用郵箱:

  • 省份:

  • 詳細(xì)地址:

  • 補(bǔ)充說(shuō)明:

  • 驗(yàn)證碼:

    請(qǐng)輸入計(jì)算結(jié)果(填寫(xiě)阿拉伯?dāng)?shù)字),如:三加四=7